Therapeutic Candidates Facilitating or Inhibiting Angiogenesis
Vessel normalization by anti-angiogenic therapeutic candidates
- Disease model : Tumor, acute/chronic inflammation, retinopathy, etc.
- Therapeutic candidates : Anti-tumor, anti-inflammatory drug, etc.
- Observations : Changes in vessel morphology, vessel diameter, vessel density, vascular permeability, blood flow rate, etc.
Angiogenesis in target cell transplanted site or ischemic regions
- Disease model : Ischemia-reperfusion injury model, islet cell/stem cell transplantation model, etc.
Efficacy Monitoring of Other Therapeutic Candidates
Changes in tumor cell growth/death/metastasis after treatment of anti-tumor therapeutic candidates
Changes in fibrotic collagen deposition & immune cell recruitment after treatment of anti-fibrotic therapeutic candidates
Changes in drug delivery, uptake & absorption